Atypical hemolytic uremic syndrome (aHUS) is a rare, life-threatening disease characterized by uncontrolled activation of the complement system—a part of the body’s immune defense. This dysregulation leads to widespread...
Cold agglutinin disease (CAD) is a type of autoimmune hemolytic anemia. Cold agglutinin disease can be separated into two subtypes: primary or secondary. Primary CAD is a chronic disorder caused by cold-reacting antibodi...
Hemolytic Disease of the Fetus and Newborn (HDFN) is also known as erythroblastosis fetalis, a rare immune-mediated disorder where maternal antibodies target fetal or newborn red blood cells (RBC’s), leading to their des...
Hemophilia is a genetic disorder where the blood lacks certain clotting proteins (factor VIII or IX), which are crucial for normal blood clotting. This deficiency results in prolonged bleeding episodes and difficulty for...
Immune thrombocytopenia (ITP) is a disorder where the body’s immune system mistakenly attacks and destroys its own platelets, which are crucial for blood clotting. This immune reaction leads to a decrease in platelet cou...
Immune Thrombocytopenic Purpura (ITP) is a rare autoimmune bleeding disorder in which the immune system mistakenly targets and destroys platelets—cells essential for blood clotting. The resulting thrombocytopenia (low pl...
Sickle cell disease is the most common genetic disease in the United States. It is an autosomal recessive disease that is characterized by sickle-shaped red blood cells in patients with anemia. Normal adult hemoglobin is...
Thalassemias are a group of inherited disorders characterized by reduced production of healthy hemoglobin and chronic anemia of varying severity. Thalassemia is caused by genetic defects in the alpha and/or beta globin g...
Thrombotic Thrombocytopenic Purpura (TTP) is a rare and life-threatening hematologic disorder characterized by widespread microvascular thrombosis due to severely reduced activity of the enzyme ADAMTS13. This deficiency...
