Adult-Onset Still’s Disease (AOSD) and sJIA
These autoinflammatory syndromes respond well to: IL-1 inhibitors (anakinra, canakinumab) IL-6 inhibitors (tocilizumab)
These autoinflammatory syndromes respond well to: IL-1 inhibitors (anakinra, canakinumab) IL-6 inhibitors (tocilizumab)
Behcet’s disease is a rare, chronic, multisystem vasculitis characterized by recurrent oral and genital ulcers, uveitis, skin lesions, and vascular, neurologic, and gastrointestinal involvement. Disease manifestations ar...
These spondyloarthropathies benefit from: IL-17 inhibitors (secukinumab, ixekizumab) IL-23 inhibitors (guselkumab, risankizumab) TNF blockade remains foundational for axial disease
Relapsing polychondritis is a rare autoimmune disease characterized by recurrent inflammation and progressive destruction of cartilaginous structures, most commonly affecting the ears, nose, tracheobronchial tree, and jo...
Early aggressive treatment guided by treat-to-target strategies has significantly reduced disability.
Research is now focused on organ-specific lupus (e.g., lupus nephritis) and precisionimmunology.
A disease marked by fibrosis and vascular injury, systemic sclerosis remains difficult to treat.
These approaches reduce steroid toxicity while maintaining disease control.