Systemic Lupus Erythematosus (SLE) is a multisystem autoimmune disease driven by immune complex deposition and interferon signaling. Recent advances include:
- Belimumab (Benlysta®) – B-cell survival inhibition
- Anifrolumab (Saphnelo®) – type I interferon receptor blockade
Research is now focused on organ-specific lupus (e.g., lupus nephritis) and precision
immunology.